Roseanne McNulty, once one of the most beautiful and beguiling girls in County Sligo, Ireland, is now an elderly patient at Roscommon Regional Mental Hospital. As her hundredth year draws near, she decides to record the events of her life, hiding the manuscript beneath the floorboards. Meanwhile, the hospital is preparing to close and is evaluating its patients to determine whether they can return to society. Dr. Grene, Roseannes caretaker, takes a special interest in her case. In his research, he discovers a document written by a local priest that tells a very different story of Roseannes life than what she recalls. As doctor and patient attempt to understand each other, they begin to uncover longburied secrets about themselves. Set against an Ireland besieged by conflict, The Secret Scripture is an epic story of love, betrayal, and unavoidable tragedy.