The Biology of Desire, Marc Lewis
The Biology of Desire, Marc Lewis
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The Biology of Desire
Why Addiction Is Not a Disease

Author: Marc Lewis

Narrator: Brent Halfyard

Unabridged: 7 hr 41 min

Format: Digital Audiobook Download

Publisher: PublicAffairs

Published: 10/07/2025

Includes: Bonus Material Bonus Material Included


Synopsis

A renowned neuroscientist provides an “unorthodox but enlightening” (Wall Street Journal) narrative of how addiction happens in the brain, and what we can do to overcome it 

Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist—and former addict himself—explains why the disease model of addiction is wrong and how it obstructs the path to recovery. Combining intimate human examples with clearly rendered scientific explanations, The Biology of Desire is enlightening and optimistic reading for anyone who has wrestled with addiction either personally or professionally. 

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Quotes

"Dr. Lewis... a former addict who recovered to become a distinguished neuroscientist and author ... writes engagingly about the addictive experience, the recovery experience and the science behind them. Whether you are looking for a foundation in the neuroscience of addiction, guidelines for recovery or just hope that recovery is possible, it's all here. The scientific information is presented in the context of day-to-day behavior and the lives of individuals you will come to care about. You'll learn more about neuroscience (and human development and psychology) than you may have thought possible. Informed by this book, you'll see how neuroscience explains addiction as a part of life, rather than a mysterious entity only experts can understand."—Tom Horvath, author of Sex, Drugs, Gambling & Chocolate: A Workbook for Overcoming Addictions

"Marc Lewis's new book neatly links current thinking about addiction with neuroscience theory and artfully selected biographies. Ex-addicts, we learn, are not 'cured'; rather they have become more connected to others, wiser, and more in touch with their own humanity. This is a hopeful message that has, as Lewis demonstrates, the advantage of also being true."—Gene Heyman, author of Addiction: Disorder of Choice

"The Biology of Desire says a lot about the brain mechanisms underpinning addiction but, to its credit, does not stop there. With minor exceptions, we do not help addicts (and they do not help themselves) by ministering directly to their brains. As Mr. Lewis stresses throughout this unorthodox but enlightening book, people learn to be addicts, and, with effort, they can learn not to be addicts, too."—Wall Street Journal

"Wonderfully readable... One finishes The Biology of Desire with... an appreciation for the argument that we may be thinking about addiction all wrong." —Washington Post

“This is the real story of ‘this is your brain on drugs,' but one that provides a refreshing, convincing alternative to the widespread traditional disease-model view of addiction. Through compelling stories of real people who struggled with various addictions, Lewis lucidly makes the case for a new science-based understanding of what causes and sustains addiction. Most important, it offers far more positivity about ways out of addiction than those offered by traditional treatment, providing hope for those struggling as well as for their loved ones.”—Anne M. Fletcher, New York Times bestselling author of Sober for Good: New Solutions for Drinking Problems

“Highly readable and plausible illustration of current ideas about addiction from behavioural neuroscience and clinical perspectives by the use of vivid case histories."—Trevor Robbins, professor of cognitive neuroscience and experimental psychology, Cambridge University

"A courageous and much needed voice in rethinking addiction—Lewis takes addiction out of a disease model and reframes it as a negative outcome of neuroplasticity—simply put, our brains' fundamental nature to change as a result of learning and experience. This model provides realistic hope, given that what has been learnt can be unlearnt by harnessing the principles of neuroplasticity. Through his intimate personal and professional knowledge of addiction Lewis reframes our understanding of its mechanisms and nature in a way that is empowering."—Barbara Arrowsmith-Young, author of The Woman Who Changed Her Brain

"So much nonsense is spoken about addiction and the brain. If you want to understand what's really happening, read Marc Lewis' clear, insightful, and necessary book."—Johann Hari, author of Chasing the Scream

"If you want to understand addiction—and why it matters how the brain actually learns to become addicted—read this book. In elegant and incisive prose, Marc Lewis expertly explains the neuroscience of desire, and how it shapes the paths of our lives."—Maia Szalavitz, author of Unbroken Brain

“Neuroscientist Lewis (Memoirs of an Addicted Brain) presents a strong argument against the disease model of addiction, which is currently predominant in medicine and popular culture alike, and bolsters it with informative and engaging narratives of addicts' lives... Even when presenting more technical information, Lewis shows a keen ability to put a human face on the most groundbreaking research into addiction. Likewise, he manages to make complex findings and theories both comprehensible and interesting… [T]his book, written with hopeful sincerity, will intrigue both those who accept its thesis and those who do not.”—Publishers Weekly