In the bustling streets of St. Louis, two cousins have a dream: to travel west with a wagon train of supplies and make a fortune in trade. Preacher needs a job and is heading west anyway. But he doesn´t bargain on the beautiful woman who sneaks her way into the wagon train and the trouble she brings on board. Then, before he can wash his hands of the whole bunch, he´s suddenly in a fight for his life. Sensing easy prey, outlaws in a lawless land have swooped down on the band of pilgrims already bitterly divided by secrets, passions and hatred. And for that, they will all answer to Preacher.